Antifungal activity of “Mahogany” ( Khaya senegalensis ) leaf extract against some selected fungi


  • Abdulaziz Bashir Kutawa Federal University Dutsin-Ma, Department of Biological Sciences, Faculty of Life Science
  • Tijjani Ahmadu Abubakar Tafawa Balewa University, Department of Crop Production, Faculty of Agriculture and Agricultural Technology
  • Amara Rafi Universiti Putra Malaysia, Institute of Plantation Studies
  • Dalhat Yusuf Federal University Dutsin-Ma, Department of Biological Sciences, Faculty of Life Science
  • Yusuf Nuradeen Garba Usmanu Danfodiyo University Sokoto, Department of Microbiology, Faculty of Chemical and Life Sciences



Antifungal, biofungicide, efficacy, fungi, leaf extract


Effect of leaf aqueous extracts of Khaya senegalensis were determined on disease causing fungi. This work aimed to determine the antifungal effect of Khaya senegalensis leaf extract on the growth of some selected fungi. In this study, the phytopathogenic fungi isolated from the spoiled bread are identified based on morphological and cultural characters. The identification of the fungi was confirmed by pathogenicity tests, the organisms were found to be Mucor spp. and Rhizopus spp. Leaf aqueous extracts of different concentrations (100, 200, 300, 400 and 500 mg mL-1) of Khaya senegalensis were added to the growth media prior to inoculation. The aqueous extracts have inhibited the mycelial growth of the fungi, and this effect gradually increased with an increase in the concentration. It could be emphatically concluded that the tested plant extract can effectively control fungi affecting. This makes it potential biofungicide for the management of fungi associated with bread as it is cheap and environmentally safe due to their fungicidal and fungitoxic ability.


Ademola, I. O., Fagbemi, B. O. & Idowu, S. O. (2004). Evaluation of the anthelmintic activity of Khaya senegalensis extract againST gastrointestinal nematodes of sheep: in vitro and in vivo studies“. Vet. Parasitol., 122(2), 151-164. DOI:

Ayandele, A. A. & Adebiyi, A. O. (2007). The phytochemical analysis and antimicrobial screening if extent of olax subscorploidee, African journal of biotechnology, 6(7), 868-870.

Bashir, K.A., Bawa, J. A. & Mohammed, I. (2014). Efficacy of leaf extract of drumstick tree (Moringa oleifera Lam.) On the growth of local tomato (Lycopersicon esculentum). Journal of Pharmacy and Biological Sciences, 9(4), 74-79. DOI:

Bashir, K. A., Kamaruzamn, S., Khairulmazmi, A, Zulkifli A. S., Mohd Shahril F. A. & Norzihan A. (2017). Characterisation and pathological variability of Exserohilum turcicum responsible for causing northern corn leaf blight (NCLB) disease in Malaysia. Malaysian Journal of Microbiology, 13(1), 41-49. DOI:

Bashir, K. A., Kamaruzamn, S., & Khairulmazmi, A. (2018a). First report of northern corn leaf blight disease caused by Exserohilum turcicum on Zea mays in Malaysia. Journal of molecular and genetic Medicine, 12(4), 1-2. DOI:

Bashir, K. A., Musa, D. D., & Aisha, A. (2018b). Antifungal activity of garlic (Allium sativum) extract on some selected fungi. Journal of Medicinal Herbs and Ethnomedicine, 4,12-14.

Bashir, K. A., Tijjani, A. & Sadi, M. J. (2020). Assessment of fungal species associated with tomato spoilage sold in Dutsin-Ma metropolis, Katsina State, Nigeria. International Journal of Agriculture, Forestry and Plantation, 10, 262-266.

Bashir, K.A., Salman, S.B., & Habu, M. (2021). Antifungal Activity of Mangifera indica Leaf Extract on Fungi Isolated from Bread Vended within Bakori, Nigeria. Innovare Journal of Agri. Sci, 9(2), 1-4. DOI:

Halama, P., & Van Haluwin C. (2004). Antifungal activity of lichen extracts and lichenic acids. Biocontrol, 49(95), 107-16. DOI:

Henry, A. Fujita, D. & Kobayashi, (2011). Physiological characterization of introgression virus derives from an indica rice. Culture field research, 112(2), 1300- 138.

Ilondu, E. M. (2012). Fungitoxic activity of leaf extracts from four Asteraceae against Sclerotium rolfsii Sacc, an isolate of sweet potato (Ipomoea batatas L.) Lam) vine rot disease. Journal of Agricultural and Biological Sciences 3(2): 287-295.

Kubmarawa, D. Khan, M. E. Punnah, A. M. Hassan, M. (2008). Phytochemical screening and Antimicrobial efficacy of axtract from khaya Senegalensis against human pathogenic bacteria. African journal of biotechnology 7(24), 023-8.

Kutawa AB, K Ahmad, A Ali, SAM Zobir, MAA Wahab (2021). Identification and characterization of pathogen responsible for causing southern corn leaf blight (SCLB) disease in Malaysia. Intl. J. Agric. Biol. 26:607‒616.

Magbool, M., Ali, A., Anderson, G. P. & Yasmenn, M. M.T. (2011). Postherviest application of gumarabic essential oil for controlling anthrax nose and quality of banana and papaya during game cold storage. Postherviest biology and technology, 62(1),71-76. DOI:

Marinho, T. A., Oliveira, M. G., Menezes-Filho, A. C. P., CastroI, C. F. S. Oliveira, M. M. Borges, L. L., Melo-Reis, P. R. and Silva-Jr, N., J. (2022). Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark. Brazilian Journal of Biology, 82, e234476 DOI:

Menezes Filho, A. C. P., de Oliveira Filho, J. G., da Cruz, R. M., da Silva, A. P., de Sousa, W. C., & de Souza Castro, C. F. (2020a). Evaluación química, fisicoquímica y actividad antifúngica de los aceites esenciales de Bauhinia variegata L. (Fabaceae). Revista Cubana de Farmacia, 53(3), 1-17.

Menezes Filho, A. C. P., de Sousa, W. C., de Oliveira Filho, J. G., & de Souza Castro, C. F. (2020b). Efecto antifúngico por el aceite esencial de las hojas y tallos de Schinus molle sobre las cepas de Aspergillus sp. Revista Cubana de Farmacia, 53(3), 1-14.

Menezes Filho, A. C. P., Ventura, M. V. A., Batista-Ventura, H. R. F., Porfiro, C. A., & de Souza Castro, C. D. F. (2021). Efecto antifúngico y citotóxico de extractos florales de Fridericia platyphylla y Fridericia florida. Revista Cubana de Farmacia, 54(4).

Menezes Filho, A. C. P., Ventura, M. V. A., de Souza Castro, C. F., Favareto, R., Belisário, C. M., Teixeira, M. B., & Soares, F. A. L. (2022). Phytochemical and physicochemical evaluation, and photoprotection, antioxidant, antifungal, and antibacterial activities of the floral extract of Schubertia grandiflora Mart. & Zucc. (Apocynaceae). Brazilian Journal of

Science, 1(1), 5-13.

Obafemi, M. D., Akinpelu, D. A., Taiwo, O. O. and Adeloye, A. (2006). Antimicrobial activity of solvent extract of Terminalia catappa lin leaves. Ife jornal of science. 8(1): 29-33. DOI:

Okigbo, R. N., and Ogbonnaya, U, O. (2006). Antifungal effects of two tropical plant leaf extracts (Ocimum gratissimum and Aframomum molegaeta) on post-harvest yam (Dioscorea spp) rot. Ife Journal of Science. 5(9):727-731.

Omar, S., Zhang, J. and MacKinnon, S. (2003). Traditionally-used antimalarials from the Meliaceae. Curr.Top.Med.Chem.Afr J (3)2: 133-139. DOI:

Paterson, L. H. Keown, S. R (2000). A new approach to hypoxia activated cancer chemotherapy, British journal of cancer 83(12), 15-89. DOI:

Ru-yong, Z., Gui-qing, C. H. Huan, and Xiao-yong Liu. (2007). A monograph of Rhizopus, syndowia an international journal of mycology. 59(2): 98-101.

Tijjani, A., Bashir, K.A., Aliyu, M., Abubakar, A.A. and Adamu, A.D. (2018a). Fungicidal efficacy of crude extracts from some indigenous plants against fungal pathogens associated with tomato (Solanum lycopersicum L.) fruit rots.

Journal of Pharmacognosy and Phytochemistry. 7(3): 1565-1570.

Tijjani, A., Bashir K. A., Gurama, A. U., Adebitan, S. A. (2018b). Potential Impact of some Cultural Practices on Incidence and Severity of Ralstonia solanacearum, Causing Bacterial Wilt Disease in Greenhouse Tomatoes. International Journal of Current Science and Studies. 2(1): 1-7.

Tijjani, A., Bashir, K.A., Jafar, S. A., Muhammad, A. and Mohammed, I. (2018c). Antifungal efficacy of some indigenous plants extract against Rhizopus stolonifer, the causal agent of wet rot disease of potato (Solanum tuberosum). Journal of Medicinal Botany. 2: 1-6.

Umeh, A. Sun, K. H. Christine, T. O. Steven, T. (2005). Pharmacokinetic profile of fyecycline in serum and skin blaster fluid of healthy subject ofter multiple intravenous administration. Antimicrobial agent and chemotherapy 49(4) 1629- 1632. DOI:

Wilkoff, B.L., James, R.C. Andrea, E. E., David, L. and Alfred, P. A. (2002). Dual - chamber pacing or ventricular backup pacing in patients with an implantable defibrillator, Journal of American medicinal association, 288(2), 3115-3123. DOI:

Williams, B. Pober, R. B. (2010). Review of Disorder, New England journal of medicine 362(3), 239-252. DOI:




How to Cite

Kutawa, A. B., Ahmadu, T., Rafi, A., Yusuf, D., & Garba, Y. N. (2022). Antifungal activity of “Mahogany” ( Khaya senegalensis ) leaf extract against some selected fungi. Brazilian Journal of Science, 1(2), 90–97.



Agrarian and Biological Sciences