Synthesis and biological evaluation of oxygen-, nitrogen-, and sulphur-containing non-fused heterocycles and tricyclic fused pyrimidines
DOI:
https://doi.org/10.14295/bjs.v4i11.810Keywords:
furo-imidazo pyrimidines, thiazolo-thieno pyrimidines, biological activity, bioactivityAbstract
A series of non-fused heterocycles containing oxygen, nitrogen, and sulfur (compounds 2, 3, 6, 9, 10, and 12), as well as furo-imidazo and thiazolo-thieno fused pyrimidines (compounds 7 and 13), were synthesized in good yields using a catalyst-free, convenient, general, and facile method. The molecular structures of all newly synthesized compounds were confirmed by spectral data and elemental microanalyses. Furthermore, the biological activities of all synthesized heterocyclic derivatives were evaluated in vitro against various common pathogenic microorganisms.
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Copyright (c) 2025 Mohammad Mizanur Rahman, Rabiul Islam, Masud Reza, Fakir Rafiqul Alam
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