Silver nanoparticles as an antibacterial agent: a literature review
DOI:
https://doi.org/10.14295/bjs.v4i8.730Keywords:
silver nanoparticle, antibacterial activity, mechanism of action, aggregationAbstract
Growing bacterial resistance to antibiotics represents a serious threat to global health. In this context, silver nanoparticles (AgNPs) have emerged as promising alternatives due to their potent antimicrobial effect and ability to inhibit biofilm formation. This study aims to evaluate the potential of AgNPs as antibacterial agents through a theoretical analysis. A qualitative systematic review was conducted on silver nanoparticles, focusing on their antimicrobial properties, using inclusion and exclusion criteria to select 27 relevant articles from the BVS and PubMed databases. The antibacterial activity of AgNPs is influenced by factors such as size, shape and stability, and they are effective at disrupting bacterial membranes and biofilms via the release of silver ions and the generation of reactive oxygen species (ROS), as well as depending on controlled conditions to optimize their efficiency and avoid aggregation. The findings indicate that AgNPs represent a promising alternative in the fight against bacterial infections, contributing significantly to the advancement of research in this area.
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