Rabies virus (RABV): cases of RABV transmission in humans registered in Brazil
DOI:
https://doi.org/10.14295/bjs.v1i10.175Keywords:
Lyssavirus genus, Bats, Canids, Anthropozoonosis, RhabdoviridaeAbstract
The transmission of the rabies virus in humans is lethal, in practically 100% of the cases. It is observed that the highest transmission rate predominates in human individuals under 15 years of age, especially in males and in urban areas. The rabies virus belongs to the Rhabdoviridae family and the Lyssavirus genus with over 16 other circumscribed virus types. The biggest sources of transmission are in the Asian and African continents. In the Americas, the rabies virus is registered from the USA to Chile, and in Brazil so far, 207 confirmed cases of rabies transmitted between non-human mammals to humans, especially dogs and bats, have been described. Public health policies with the vaccination of domestic animals against rabies showed a significant drop in cases of transmission, although the target source is still wild bats, mainly of the Desmodus genus, however, several studies show that other classes of bats with non-hematophagous habits are hosts of the rabies virus. In addition to great concern about the 2019-Current Covid-19 pandemic and the emergence of cases in more than 90 countries of Monkeypox (Mamacopox) we must now be concerned about the increase in human rabies cases and its lethality. Cases in Brazil show heterogeneity between the years of confirmed cases, although we must worry about controlling and educating the population and investigating fomites carrying the virus.
References
Aldrich, C., Leroux-Roels, I., Huang, K. B., Bica, M. A., Loeliger, E., Schoenborn-Kellenberger, O., Walz, L., Leroux-Roels, G., von Sonnenburg, F. & Oostvogels, L. (2021). Proof-of-concept of a low-dose unmodified mRNA-based rabies vaccine formulated with lipid nanoparticles in human volunteers: a phase 1 trial. Vaccine, 39(8), 1310-1318. https://doi.org/10.1016/j.vaccine.2020.12.070 DOI: https://doi.org/10.1016/j.vaccine.2020.12.070
Baer, G. M. (1975). Rabies in nonhematophagous bats. In: Baer, G. M. The natural history of rabies. New York: Academic Press, 79-97 p.
Batista, H. B. C. R., Franco, A. C. & Roehe, P. M. (2007). Raiva: uma breve revisão. Acta Scientiae Veterinariae, 35(2), 125-144. https://doi.org/10.22456/1679-9216.15959 DOI: https://doi.org/10.22456/1679-9216.15959
Brasil – Ministério da Saúde. (2022). Raiva. [cited on August 02, 2022]. Available from: https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/r/raiva#:~:text=Foram%20notificados%202%20casos%20de%20raiva%20humana%20no,mulher%20de%2068%20anos%2C%20agredida%20por%20uma%20raposa.
Caraballo, D. A., Lema, C., Novaro, L., Gury-Dohmen, F., Russo, S., Beltrán, F. J., Palacios, G. & Cisterna, D. M. (2021). A novel terrestrial rabies virus lineage occurring in South America: origin, diversification, and evidence of contact between wild and domestic cycles. Viruses, 13(12), 2484. https://doi.org/10.3390/v13122484 DOI: https://doi.org/10.3390/v13122484
Dias, R. A., Filho, V. S. N., Goulart, C. S., Telles, I. C. O., Marques, G. H. F., Amaku, F. F. M. & Neto, J. S. F. (2011). Modelo de risco para circulação do vírus da raiva em herbívoros no Estado de São Paulo, Brasil. Revista Panamericana de Salud Publica, 30(4), 370-376. https://scielosp.org/article/rpsp/2011.v30n4/370-376/
Duarte, N. F. H., Neto, R. J. P., Viana, V. F., Feijão, L. X., Abreu, K. G., Melo, I. M. L. A., Sousa, A. Q., Alencar, C. H. &
Heukelbach, J. (2021). Epidemiologia da raiva humana no estado do Ceará, 1970 a 2019. Revista Epidemiologia e Serviços de Saúde, 30(1), e2020354. https://doi.org/10.1590/S1679-49742021000100010 DOI: https://doi.org/10.1590/s1679-49742021000100010
Haupt, H. & Rehaag, H. (1925). Raiva epizoótica nos rebanhos de Santa Catarina, sul do Brasil, transmitida por morcegos. Boletim da Sociedade Brasileira de Medicina Veterinária, 2, 17-47.
Hayes, M. A., & Piaggio, A. J. (2018). Assessing the potential impacts of a changing climate on the distributuin of a rabies virus vector. PLoS ONE, 13(2), e0192887. https://doi.org/10.1371/journal.pone.0192887 DOI: https://doi.org/10.1371/journal.pone.0192887
Kotait, I., Oliveira, R. N., Carrieri, M. L., Castilho, J. G., Macedo, C. I., Pereira, P. M. C., Boere, V., Montebello, L. & Rupprecht, C. E. (2019). Non-human primates as a reservoir rabies virus in Brazil. Zoonoses and Public Health, 66(1), 47-59. https://doi.org/10.1111/zph.12527 DOI: https://doi.org/10.1111/zph.12527
Kotait, I., Carrieri, M. L., Carnieli Júnior, P., Castilho, J. G., Oliveira, R. N., Macedo, C. I., Ferreira, K. C. S. & Achkar, S. M. (2007). Reservatórios silvestres do vírus da raiva: um desafio para a saúde pública. BEPA, Boletim Epidemiológico Paulista, 4(40), 2-8. https://www.researchgate.net/publication/233992237_Reservatorio_Silvestre_do_virus_da_raiva_um_desafio_para_saude_publica
Meske, M., Fanelli, A., Rocha, F., Awada, L., Soto, P. C., Mapitse, N. & Tizzani, P. (2021). Evolution of rabies in South America and inter-species dynamics (2009-2018). Tropical Medicine and Infectious Disease, 6(2), 98. https://doi.org/10.3390/tropicalmed6020098 DOI: https://doi.org/10.3390/tropicalmed6020098
Quevedo, L. S., Hugen, G. G. P., Morais, R. M. & Quevedo, P. S. (2020). Aspectos epidemiológicos, clínicos-patológicos e diagnóstico de raiva em animais de produção: Revisão. PUBVET, 14(11), 1-11. http://dx.doi.org/10.31533/pubvet.v14n11a690.1-11 DOI: https://doi.org/10.31533/pubvet.v14n11a690.1-11
Scheffer, K. C., Carrieri, M. L., Albas, A., Santos, H. C. P., Kotait, I. & Ito, F. H. (2007). Vírus da raiva em quirópteros naturalmente infectados no Estado de São Paulo, Brasil. Revista Saúde Pública, 41(3), 389-395. https://doi.org/10.1590/S0034-89102007000300010 DOI: https://doi.org/10.1590/S0034-89102007000300010
Shipley, R., Wright, E., Lean, F. Z. X., Selden, D., Horton, D. L., Fooks, A. R. & Banyard, A. C. (2021). Assessing rabies vaccine protection against a novel Lyssavirus, Kotalahti bat Lyssavirus. Viruses, 13(5), 947. https://doi.org/10.3390/v13050947 DOI: https://doi.org/10.3390/v13050947
Schreiber, M. S. & Fachinetto, J. M. (2021). Relaçãoo filogenética do vírus da raiva (Rabies Lyssavirus) em dois diferentes hospedeiros. In: Salão do Conhecimento, Unijuí, 2021, 26-29 de Outubro de 2021, 1-5 p.
Vargas, A., Romano, A. P. M. & Merchán-Hamann, E. (2019). Raiva humana no Brasil: estudo descritivo, 2000-2017. Revista Epidemiologia e Serviços de Saúde, 28(2), e2018275. https://doi.org/10.5123/S1679-49742019000200001 DOI: https://doi.org/10.5123/S1679-49742019000200001
Yang, D-K., Kim, H-H., Lee, K-W. & Song, J-Y. (2013). The present and future of rabies vaccine in animals. Clinical and Experimental Vaccine Research, 2(1), 19-25. https://doi.org/10.7774/cevr.2013.2.1.19 DOI: https://doi.org/10.7774/cevr.2013.2.1.19
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