Essential oil from the petioles of Protium ovatum Engl. (Burseraceae) has bioactive and antifungal activity?
DOI:
https://doi.org/10.14295/bjs.v1i7.151Keywords:
Protium ovatum, Candida albicans, Antioxidant activity, Candida kruseiAbstract
Protium ovatum is a specie present in the most varied types from Cerrado in Brasil, and this specie is reconoced as a phytotherapeutic plant. The objective of the study was to characterize chemically and biologically the essential oils of Protium ovatum petioles collected in three areas of the Cerrado in the state of Goiás, Brasil. Petioles were collected in three areas of savanna Cerrado. The essential oil was extracted in Clevenger, the yield determined in percentage. Physicochemical analyzes were performed for chemical composition by gas chromatography with mass emitter, relative density, solubility, refractive index and optical rotation. To determine the biological antioxidant activity, the DPPH was used, and determined in IC50, and the antifungal activity performed by diluting the essential oil in the disc diffusion method. Essential oils showed a yield of 0.35; 0.44 and 0.29%, density of 0.905; 0.907 and 0.912 g mL-1, positive solubility, refractive index of 1.3881; 1.3853 and 1.3799, optical rotation of +40.6; +40.9 and +39.8 αD, and IC50 of 1.67; 1.57 and 2.19 µL mL-1, for Cerradão, Cerrado rupestre and Cerrado sujo, respectively. There were about 12 major compounds and exceptional antifungal activity against Candida isolates. Essential oils presented as a new antioxidant and antifungal source against Candida isolates. The physicochemical characteristics similar to other essential oils in the literature. The phytophysiognomic characteristics should in the future be evaluated through genetic analysis between groups of individuals in the three study areas.
References
Adams, R. P. Identification of essential oil components by gas chromatography/mass spectrometry. 4th Edition. Allured Publishing Corporation, Illinois.
Alarcón, M. E. T., Conde, C. G. & Méndez, G. L. (2019). Extraccíon, caracterización y actividad antioxidante del aceite esencial de Eucalyptus globulus Labill. Revista Cubana de Farmacia, 52(1), e266.
Cabral, R. S. C., Alves, C. C. F., Batista, H. R. F., Sousa, W. C., Abrahão, I. S., Crotti, A. E. M., Santiago, M. B., Martins, C. H. G. & Miranda, M. L. D. (2018). Chemical composition of essential oils from different parts of Protium heptaphyllum (Aubl.) Marchand and their in vitro antibacterial activity. Natural Product Research, 34(16), 2378-2383. DOI: https://doi.org/10.1080/14786419.2018.1536659
Carneiro, N. S., Alves, J. M., Alves, C. C. F., Esperandim, V. R. & Miranda, M. L. D. (2017). Óleo essencial das flores de Eugenia klotzschiana (Myrtaceae): composição química e atividades tripanocida e citotóxica in vitro. Revista Virtual de Química, 9(3), 1381-1392. DOI: https://doi.org/10.21577/1984-6835.20170080
Castelo, A. V. M., Menezzi, C. H. S. D. & Resck, I. S. (2010). Rendimento e análises espectroscópicas (RMN 1H, 13C, IV) da composição química dos óleos essenciais de quatro plantas do Cerrado. Cerne, 16, 573-584. DOI: https://doi.org/10.1590/S0104-77602010000400017
Dias, M. O., Hamerski, L. & Pinto, A. C. (2011). Separação semipreparativa de α e β-amirina por cromatografia líquida de alta eficiência. Química Nova, 34, 704-706. DOI: https://doi.org/10.1590/S0100-40422011000400026
Estevam, E. B. B., Alves, C. C. F., Esperandim, V. R., Cazal, C. M., Souza, A. F. & Miranda, M. L. D. (2018). Chemical composition, anti-Trypanossoma cruzi and cytotoxic activities of the essential oil from green fruits of Protium ovatum (Burseraceae). Revista Brasileira de Fruticultura, 40(1), e-794. DOI: https://doi.org/10.1590/0100-29452018794
Estevam, E. B. B., Deus, I. P. B., Silva, V. P., Silva, E. A. J., Alves, C. C. F., Alves, J. M., Cazal, C. M., Magalhães, L. G., Pagotti, M. C., Esperandim, V. R., Souza, A. F. & Miranda, M. L. D. (2017). In vitro antiparasitic and chemical composition of the essential oil from Protium ovatum leaves (Burseraceae). Anais da Academia Brasileira de Ciências, 89(4), 3005-3015. DOI: https://doi.org/10.1590/0001-3765201720170310
He, X., Ma, Y., Yi, G., Wu, J., Zhou, L. & Guo, H. (2017). Chemical composition and antifungal activity of Carica papaya Linn. seed essential oil against Candida spp. Letters in Applied Microbiology, 64(5), 350-354. DOI: https://doi.org/10.1111/lam.12711
Menezes Filho, A. C. P. & Castro, C. F. S. (2020). Avaliação físico-química e atividade antifúngica do óleo essencial de Myrocarpus fastigiatus e óleo-resina de Copaifera multijuga. Arquivos Científicos, 3(1), 117-123. DOI: https://doi.org/10.5935/2595-4407/rac.immes.v3n1p117-123
Mezza, G. N., Borgarello, A. V., Grosso, N. R., Fernandez, H., Pramparo, M. C. & Gayol, M. F. (2018). Antioxidant activity of rosemary essential oil fractions obtained by molecular distillation and their effect on oxidative stability of sunflower oil. Food Chemistry, 242, 9-15. DOI: https://doi.org/10.1016/j.foodchem.2017.09.042
Moraes, M. M., Camara, C. A. G. & Ramos, C. S. (2013). Seasonal variation in the essential oil of Protium bahianum Daly (Burseraceae). Journal of Essential Oil Bearing Plants, 16, 300-307. DOI: https://doi.org/10.1080/0972060X.2013.813218
Moura, A. S., Machado, F. S., Cortez, E. A., Leite, L. H., Mariano, R. F. & Fontes, M. A. L. (2022). Localidades de Ocorrência do globalmente ameaçado de extinção galito, Alectrurus tricolor (Passeriformes: Tyrannidae), em regiões de ecótono Cerrado/florestas Atlântica do Sul do Estado de Minas Gerais, Brasil. Regellea Scientia, 8(1), 14-22.
Oliveira, L. B. S.; Batista, A. H. M.; Fernandes, F. C.; Sales, G. W. P. & Nogueira, N. A. P. (2016). Atividade antifúngica e possível mecanismo de ação do óleo essencial de folhas de Ocimum gratissimum (Linn.) sobre espécies de Candida. Revista Brasileira de Plantas Medicinais, 18(2), 511-523. DOI: https://doi.org/10.1590/1983-084X/15_222
Oliveira, C. F., Bobek, V. B., Pietruchinski, E. & Cardozo, A. G. L. (2015). Avaliação da atividade antifúngica do óleo essencial de Baccharis dracunculifolia DC. frente à levedura da espécie Candida albicans. Visão Acadêmica, 16(4), 4-11. DOI: https://doi.org/10.5380/acd.v16i4.44118
Oliveira Lima, I., Oliveira, R., Oliveira Lima, E., Farias, N. M. P. & Souza, E. L. (2006). Atividade antifúngica de óleos essenciais sobre espécies de Candida. Brazilian Journal of Pharmacognosy, 16(2), 197-201. DOI: https://doi.org/10.1590/S0102-695X2006000200011
Pimenta, E. S., Da Cruz, R. M. C., Diniz Neto, H., Silva, D. F., Oliveira, H. M. B. F., Buccini, D. F., Lima, E. O., Oliveira Filho, A. A. (2019). Avaliação da atividade antifúngica do óleo essencial de Pogostemon cablin (Blanco) Benth. (Lamiaceae) contra cepas de Candida glabrata. Scientia Plena, 15(6), 1-5. DOI: https://doi.org/10.14808/sci.plena.2019.064601
Rivera, P. N., Paredes, E. A., Gómez, E. D., Lueckhoff, A., Almeida, G. A. & Suarez, S. E. (2017). Composición química y actividad antimicrobiana del aceite esencial de los rizomas de Renealmia thyrsoidea (Ruiz & Pav) Poepp. & Eddl. (shiwanku muyu). Revista Cubana de Plantas Medicinales, 22(2).
Santos, M. R. A., Lima, R. A., Silva, A. G., Lima, D. K. S., Sallet, L. A. P., Teixeira, C. A. D. & Facundo, V. A. (2013). (Composição química e atividade inseticida do óleo essencial de Schinus terebinthifolius Raddi (Anacardiaceae) sobre a broca-do-café (Hypothenemus hampei) Ferrari. Revista Brasileira de Plantas Medicinais, 15(4), 757-762. DOI: https://doi.org/10.1590/S1516-05722013000500017
Santos, T. G., Rebelo, R. A., Dalmarco, E. M., Guedes, A., De Gasper, A. L., Cruz, A. B., Schmit, A. P., Cruz, R. C. B., Steindel, M. & Nunes, R. K. (2012). Composição química e avaliação da atividade antimicrobiana do óleo essencial das folhas de Piper malacophyllum (C. Presl.) C. DC. Revista Química Nova, 35(3), 477-481. DOI: https://doi.org/10.1590/S0100-40422012000300007
Tahvilian, R., Moradi, R., Zhale, H., Zangeneh, M. M., Zangeneh, A., Yazdani, H. & Hajialiani, M. (2016). Ethnomedicinal Plants: Study on antifungal activity of essential oil of Pistacia khinjuk (combined with the dominance γ-terpinene) against Candida albicans. International Journal of Pharmaceutical and Clinical Research, 8(10), 1369-1373.
Teixeira, P. R.; Ferreira, R. Q. S.; Camargo, M. O.; Silva, R. R. & Souza, P. B. (2016). Produção de serapilheira de duas fisionomias do domínio Cerrado, Gurupi, Tocantins. Revista Verde de Agroecologia e Desenvolvimento Sustentável, 11(5), 45-50. DOI: https://doi.org/10.18378/rvads.v11i5.4283
Torrenegra-Alarcón, M.; Granados-Conde, C.; Durán-Lengua, M.; León-Méndez, G.; Yáñez-Rueda, X.; Martínez, C. & Pájaro-Castro, N. (2016). Composición química y actividad antibacteriana del aceite esencial de Minthostachys mollis. Orinoquia, 20(1), 69-74. DOI: https://doi.org/10.22579/20112629.329
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Wendel Cruvinel de Sousa, Antonio Carlos Pereira de Menezes Filho, Cássia Cristina Fernandes Alves, Marcela Cristofoli, Cristiane de Melo Cazal, Moacir Rossi Forim, Matheus Vinicius Abadia Ventura, Aparecida Sofia Taques, Ivan Alves, Carlos Frederico de Souza Castro
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
