Phytochemical screening and cytotoxic activity of latex from Manilkara zapota (L.) P. Royen

Authors

  • Antonio Carlos Pereira de Menezes Filho Instituto Federal Goiano, Rio Verde, Goiás, Brasil
  • Matheus Vinicius Abadia Ventura Laboratório de Microbiologia Agrícola, Instituto Federal Goiano, Rio Verde, Goiás State, Brasil
  • Hellen Regina Fernandes Batista-Ventura 4Laboratório de Análide de Solo, Tecido e Foliar, Instituto Federal Goiano, Rio Verde, Goiás State, Brasil
  • Carlos Frederico de Souza Castro Laboratório de Química Tecnológica, Instituto Federal Goiano, Rio Verde, Goiás State, Brasil
  • Marconi Batista Teixeira Laboratório de Hidráulica e Irrigação, Instituto Federal Goiano, Rio Verde, Goiás State, Brasil
  • Frederico Antônio Loureiro Soares Laboratório de Hidráulica e Irrigação, Instituto Federal Goiano, Rio Verde, Goiás State, Brasil

DOI:

https://doi.org/10.14295/bjs.v1i7.150

Keywords:

Manilkara genus, Artemia salina, Special metabolites, Fruit trees, Biological activities

Abstract

Manilkara zapota fruiting species from tropical and tropical areas present latex as a product of special metabolism, with pharmacological properties. This study aimed to evaluate the qualitative phytochemical composition and toxicological activity on Artemia salina evaluated at different concentrations of the extract collected from the pedicel of the fruit of M. zapota. The latex was collected and immediately, the solubility in different polar and nonpolar solvents, the phytochemical prospection using different reagents and the toxicity assay on A. salina larvae in different concentrations of latex were performed. The latex showed solubility results only for water and ethanol. Several phytochemical classes were observed with positive results, especially for flavonoids, phenolics, steroids and saponins. The toxicological test on A. salina showed a lethal dose of 17.9 µg mL-1, considered moderate. Manilkara zapota latex has shown great aptitude for new quantitative and evaluation studies for other biological models.

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Published

2022-07-01

How to Cite

Menezes Filho, A. C. P. de, Ventura, M. V. A., Batista-Ventura, H. R. F., Castro, C. F. de S., Teixeira, M. B., & Soares, F. A. L. (2022). Phytochemical screening and cytotoxic activity of latex from Manilkara zapota (L.) P. Royen. Brazilian Journal of Science, 1(7), 12–25. https://doi.org/10.14295/bjs.v1i7.150

Issue

Vol. 1 No. 7 (2022): Brazilian Journal of Science

Section

Agrarian and Biological Sciences

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Copyright (c) 2022 Antonio Carlos Pereira de Menezes Filho, Silvia Rosana Pagliarini Cabral

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